Benzoyl Peroxide → HCID 19858052, compound

HRID 2073388Notes

Reaction equation

HRID 2073388 reaction equation
[CH3:1][C:2]1([CH3:19])[C:6](=[O:7])[O:5][C:4]2[CH:8]=[CH:9][C:10]3[C:15]([C:3]1=2)=[CH:14][C:13]([CH3:16])=[C:12]([C:17]#[N:18])[CH:11]=3.[Br:20]N1C(=O)CCC1=O.C(OOC(=O)C1C=CC=CC=1)(=O)C1C=CC=CC=1>C(Cl)(Cl)(Cl)Cl>[Br:20][CH2:16][C:13]1[CH:14]=[C:15]2[C:10]([CH:9]=[CH:8][C:4]3[O:5][C:6](=[O:7])[C:2]([CH3:19])([CH3:1])[C:3]=32)=[CH:11][C:12]=1[C:17]#[N:18]

Participants

5

Reactant 3

HCID 7187Benzoyl PeroxideHCID 67184N-bromobutanimideHCID 19858070HCID 19858070, compound

Product 1

HCID 19858052HCID 19858052, compound

Reagents, catalysts & solvents 1

HCID 5943Carbon TetrachlorideSolvent

Procedure

A mixture of 1,2-dihydro-1,1,8-trimethyl-2-oxonaphtho[2,1-b]furan-7-carbonitrile, (0.25 g), N-bromosuccinimide (0.2 g), benzoyl peroxide (0.01 g) and carbon tetrachloride (40 ml) was stirred under reflux for 24 h. The reaction mixture was cooled, washed with water, dried and evaporated to dryness under reduced pressure, to give the required starting material, 8-bromomethyl-1,2-dihydro-1,1-dimethyl-2-oxonaphtho[2,1-b]furan-7-carbonitrile, which was used without further purification.

Workup

  1. temperatureunder reflux for 24 h
  2. temperatureThe reaction mixture was cooled
  3. washwashed with water
  4. customdried
  5. customevaporated to dryness under reduced pressure

Sources & evidence

ORD record
ord-d6e88b7ab9ea4d279e7cdea699f3ef18
Source dataset
uspto-grants-1990_04
Patent number
US04916148

Reaction notes

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