Ethanol → HCID 19858066, compound

Participants

Reaction Steps

A solution of 2-chloro-1,2-dihydro-1,1-dimethyl-8-(1H-1,2,4-triazol-1-ylmethyl)naphtho[2,1-b]furan-7-carbonitrile in ethanol (5 ml) was treated with triethylamine (0.06 ml), and the mixture was kept at room temperature for 3 h and then evaporated to dryness under reduced pressure. The residue was purified by flash chromatography, using methanol:dichloromethane, 1:200 v/v as eluant, to give 2-ethoxy-1,2-dihydro-1,1-dimethyl-8-(1H-1,2,4-triazol-1-ylmethyl)naphtho[2,1-b]-furan-7-carbonitrile, m.p. 128°-129°.

Provenance & Evidence