HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2073414Generated: November 1, 2026
Chloroacetic Acid → Glycine, N-(3-hydroxyphenyl)-
https://huagongshe.com/reaction/2073414
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Chloroacetic Acid | HCID 300 | — |
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | 3-Aminophenol | HCID 11568 | — |
| Reactant | Lithium hydroxide, monohydrate | HCID 168937 | — |
| Reactant | Lithium | HCID 3028194 | — |
| Solvent | Water | HCID 962 | — |
| Product | Glycine, N-(3-hydroxyphenyl)- | HCID 5318318 | — |
Reaction Steps
9.2 g of monochloroacetic acid are introduced into 40 ml of water and converted into the lithium salt with 4.1 g of lithium hydroxide monohydrate. 10.4 g of 3-aminophenol are then added and the mixture is stirred at 90° C. for 2 hours. It is then cooled to 20° C. and brought to pH 7 with sodium carbonate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04917731 |
|---|
| Source dataset | uspto-grants-1990_04 |
|---|
| ORD ID | ord-1d45e455a716486db05363252e164d61 |
|---|
| Source note | uspto-grants-1990_04 |
|---|