HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Nitrophenol → 6-nitro-3,4-dihydro-2H-1-benzopyran-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Nitrophenol | HCID 980 | — |
| Reactant | Acrylic Acid | HCID 6581 | — |
| Reactant | Phenothiazine | HCID 7108 | — |
| Reactant | Hydrofluoric Acid | HCID 14917 | — |
| Product | 6-nitro-3,4-dihydro-2H-1-benzopyran-4-one | HCID 5228831 | — |
Reaction Steps
Following the same procedure as Example 1, p-nitrophenol (34.8 grams), acrylic acid (27 grams), and an inhibitor, phenothiazine (0.02 grams was added to the pressure reactor. The anhydrous hydrogen fluoride (110 grams) was added before the system was warmed. When the reaction temperature was attained, a pressure of 140 psig was noted, similar to previous reactions. Work-up was carried out as previous examples and the 6-Nitro-4-Chromanone was isolated and characterized.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04918203 |
| Source dataset | uspto-grants-1990_04 |
| ORD ID | ord-ce1370dc184546b8b46c5892973bcee1 |
| Source note | uspto-grants-1990_04 |