Chlorotrimethylsilane → HCID 14371698, compound

Participants

Reaction Steps

2 g (4.5 millimoles) of diethyl (E)-4-[2(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)-1propenyl]-benzenephosphonate, 1.86 g (18 millimoles) of sodium bromide and 3 g (27 millimoles) of trimethylchlorosilane in 10 ml of acetonitrile were stirred for 3 hours at 40° C. The mixture was then allowed to cool and was filtered, and the filtrate was evaporated down. The oil which remained was stirred for 30 minutes with water at room temperature and then extracted with ether, and the organic phase was washed with water, dried over sodium sulfate and evaporated down. Recrystallization of the residue from ethyl acetate gave 1.1 g of the title compound of melting point 208°-209° C.

Provenance & Evidence