HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Acid → HCID 86743864, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | 3-Nitrobenzaldehyde | HCID 7449 | — |
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | Acetoacetamide | HCID 80077 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | HCID 86743864 | HCID 86743864 | 117.5% |
Reaction Steps
A mixture of 10 g of acetoacetamide and 15 g of 3-nitrobenzaldehyde in 100 ml of isopropanol is stirred at 35° C. for 4 hours in the presence of 0.3 ml of piperidine and 0.5 ml of acetic acid. The precipitated yellow crystals are collected by filtration to give 20 g of α-acetyl-3-nitrocrotonamide, melting at 159°-161° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04918074 |
| Source dataset | uspto-grants-1990_04 |
| ORD ID | ord-c975d2b0f949443aae1ee2cd7c1076b5 |
| Source note | uspto-grants-1990_04 |