HuagongsheHuagongshe Chemistry Print Report · For research reference only
Styrene → HCID 5162089, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Styrene | HCID 7501 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 4-Bromobenzoic acid | HCID 11464 | — |
| Reactant | 4-(2-Phenylethenyl)benzoyl chloride | HCID 53817288 | — |
| Catalyst | Tri-o-tolylphosphine | HCID 80271 | — |
| Catalyst | palladium(II) acetate | HCID 167845 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Product | HCID 5162089 | HCID 5162089 | 55% |
Reaction Steps
Stilbene-4-carboxylic acid chloride can be prepared as follows: 25.15 g (125 mmols) of 4-bromobenzoic acid, 16.25 g (156.25 mmols) of styrene, 26.55 g (262.5 mmols) of triethylamine, 0.28 g (1.25 mmols) of palladium acetate and 1.52 g (5 mmols) of tri-o-tolylphosphine are stirred at 100° C. for 3.5 hours. The reaction mixture is poured into 100 ml of 2N HCl and the crude product is filtered off and recrystallised from tetrahydrofuran/toluene. 15.3 g (55% of theory) of stilbene-4-carboxylic acid are obtained in the form of white crystals; melting point 252.4° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04918215 |
| Source dataset | uspto-grants-1990_04 |
| ORD ID | ord-39455c6a9dd84a149c30a8fe2ef0ba3a |
| Source note | uspto-grants-1990_04 |