HuagongsheHuagongshe Chemistry Print Report · For research reference only
Toluene → HCID 54300281, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Toluene | HCID 1140 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | HCID 54303311 | HCID 54303311 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 54300281 | HCID 54300281 | 79% |
Reaction Steps
14.8 g (67 mmols) of ethyl 4-carboxycinnamate, 9.57 g (80 mmols) of thionyl chloride, 100 ml of toluene and 0.18 ml of N,N-dimethylformamide are boiled under reflux for 30 minutes. The reaction mixture is evaporated and the crude product is recrystallised from n-hexane. 12.6 g (79% of theory) of ethyl 4-chloroformylcinnamate are obtained in the form of white crystals; melting point 76.8° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04918215 |
| Source dataset | uspto-grants-1990_04 |
| ORD ID | ord-ab7174e070c74254933145506e7b09e9 |
| Source note | uspto-grants-1990_04 |