Hydrochloric Acid → HCID 54344969, compound

Participants

Reaction Steps

27.5 g (0.2 mole) 4-chlorobenzonitrile, 29.8 g (0.2 mole) D-penicillamine and 13.8 g (0.1 mole) potassium carbonate were heated in 350 ml methanol and 150 ml water for 6 hours at the boiling point. After the mixture was acidified with concentrated hydrochloric acid to pH 4, it was heated one hour under nitrogen at the boiling point. After it cooled off, 42.6 g (74% of theory) of a colorless precipitate was isolated, which had a melting point of 174° C.

Provenance & Evidence