HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → HCID 15057240, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | HCID 23706480 | HCID 23706480 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 15057240 | HCID 15057240 | — |
Reaction Steps
To 100 mL of thionyl chloride at 0° C. is added 25.1 g (0.1 mol) of 4-[(ethylsulfonyl)amino]benzoic acid sodium salt (prepared from the acid and sodium hydroxide in water and evaporation of solvent) under a nitrogen atmosphere. Reflux the reaction mixture for 24-40 hr. then remove the excess thionyl chloride in vacuo. Dissolve the crude material in tetrahydrofuran, filter through celite and evaporate the solvent to obtain the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04920116 |
| Source dataset | uspto-grants-1990_04 |
| ORD ID | ord-6ef28d7c3cdc47759ccefda90131641d |
| Source note | uspto-grants-1990_04 |