Formaldehyde → HCID 53949975, compound

HRID 2073726Notes

Reaction equation

HRID 2073726 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([F:8])[C:3]=1[CH2:9][C:10]#[N:11].Cl.[NH:13]1[CH2:18][CH2:17][O:16][CH2:15][CH2:14]1.[CH2:19]=O>>[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([F:8])[C:3]=1[CH:9]([CH2:19][N:13]1[CH2:18][CH2:17][O:16][CH2:15][CH2:14]1)[C:10]#[N:11]

Participants

4

Reactant 3

HCID 712FormaldehydeHCID 69559(2,6-Difluorophenyl)acetonitrileHCID 197884Morpholine, hydrochloride (1:1)

Product 1

HCID 53949975HCID 53949975, compound

Procedure

In a manner similar to Preparation 11 react 2,6-difluorobenzeneacetonitrile with morpholine hydrochloride and paraformaldehyde to obtain the title compound.

Workup

  1. customIn a manner similar to Preparation 11

Sources & evidence

ORD record
ord-f2148d43290242ff917136d6697f59dd
Source dataset
uspto-grants-1990_04
Patent number
US04920116

Reaction notes

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