Chloroacetyl chloride → HCID 15057230, compound
Reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([NH2:8])=[CH:4][CH:3]=1.Cl[CH2:10][C:11](Cl)=[O:12].[C:14]1([CH2:20][NH:21][CH2:22][CH2:23][C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1>>[F:1][C:2]1[CH:7]=[CH:6][C:5]([NH:8][C:11](=[O:12])[CH2:10][N:21]([CH2:22][CH2:23][C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)[CH2:20][C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)=[CH:4][CH:3]=1Participants
4
Procedure
In a manner similar to Preparation 1 react 4-fluorobenzenamine with chloroacetyl chloride followed by N-(phenylmethyl)benzeneethanamine to obtain the title compound.
Workup
- customIn a manner similar to Preparation 1
Sources & evidence
- ORD record
- ord-9a1b523d1ce84cd5a9a956c223193574
- Source dataset
- uspto-grants-1990_04
- Patent number
- US04920116
Reaction notes
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