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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2073878Generated: November 1, 2026

3-Hydroxybenzaldehyde → HCID 10422857, compound

https://huagongshe.com/reaction/2073878

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-HydroxybenzaldehydeHCID 101—
ReactantWaterHCID 962—
ReactantPotassium CarbonateHCID 11430—
Reactant2-(Chloromethyl)quinolineHCID 20394—
SolventDimethylformamideHCID 6228—
ProductHCID 10422857HCID 10422857—

Reaction Steps

A solution of 0.65 g (5.4 mmol) 3-hydroxybenzaldehyde, 0.94 g (5.3 mmol) of 2quinolinylmethylchloride, and 0.75 g (5.4 mmol) of potassium carbonate in 15 ml of DMF is heated at 60° C. overnight. The reaction mixture is poured into water. The precipitated product is collected on a filter and purified by dry column chromatography to give 3-(2-quinolinylmethyloxy)benzaldehyde.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04920133
Source datasetuspto-grants-1990_04
ORD IDord-5c79a403db28410da70d2a235882e4ce
Source noteuspto-grants-1990_04