HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2073897Generated: October 30, 2026
O-Cresol → Ethyl 2-(2-methylphenoxy)propionate
https://huagongshe.com/reaction/2073897
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | O-Cresol | HCID 335 | — |
| Reactant | Water | HCID 962 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Ethyl 2-bromopropionate | HCID 79040 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | Ethyl 2-(2-methylphenoxy)propionate | HCID 10398141 | — |
Reaction Steps
A mixture of 10.8 g (0.1 mol) of o-cresol, 18.1 g (0.1 mol) of ethyl 2-bromopropionate, and 14.5 g of K2CO3 in 50 ml of DMF is heated at 70° C. for 3 days. The reaction mixture is poured into H2O, and extracted with ethyl acetate. The organic solution is dried and evaporated to give ethyl 2-(2-methylphenoxy)propionate which is used directly in the next step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04920131 |
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| Source dataset | uspto-grants-1990_04 |
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| ORD ID | ord-f949238c31f447f9a52b0b061efe7b60 |
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| Source note | uspto-grants-1990_04 |
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