HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Chlorothieno[3,2-b]pyridine-5,6-dicarboxylic acid → 3-Chlorothieno[3,2-b]pyridine-5,6-dicarboxylic acid anhydride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Chlorothieno[3,2-b]pyridine-5,6-dicarboxylic acid | HCID 14838728 | — |
| Solvent | Acetic Anhydride | HCID 7918 | — |
| Product | 3-Chlorothieno[3,2-b]pyridine-5,6-dicarboxylic acid anhydride | HCID 13752485 | 89% |
Reaction Steps
3-Chlorothieno[3,2-b]pyridine-5,6-dicarboxylic acid (1.45 g) is heated at 85° to 90° C. for 30 minutes then 90° to 102° C. for 30 minutes in acetic anhydride (7 mL). The reaction is cooled, the solids filtered off and washed with ether to give 1.2 g of 3-chlorothieno[3,2-b]pyridine-5,6-dicarboxylic acid anhydride. The proton magnetic resonance spectrum is consistant with the structure.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04920226 |
| Source dataset | uspto-grants-1990_04 |
| ORD ID | ord-d36e90e6570340948e2cfd8d5d98e5e1 |
| Source note | uspto-grants-1990_04 |