Furo[2,3-b]pyridine → HCID 13849587, compound

HRID 2073985Notes

Reaction equation

HRID 2073985 reaction equation
[O:1]1C2=NC=CC=C2C=C1.[CH:10]([C:13]1([CH3:31])[C:17](=[S:18])[NH:16][C:15]([C:19]2[N:24]=[C:23]3S[CH:26]=[CH:27][C:22]3=[CH:21][C:20]=2[C:28]([OH:30])=[O:29])=[N:14]1)([CH3:12])[CH3:11]>>[CH:10]([C:13]1([CH3:31])[C:17](=[S:18])[NH:16][C:15]([C:19]2[N:24]=[C:23]3[O:1][CH:26]=[CH:27][C:22]3=[CH:21][C:20]=2[C:28]([OH:30])=[O:29])=[N:14]1)([CH3:12])[CH3:11]

Participants

3

Reactant 2

HCID 12421098Furo[2,3-b]pyridineHCID 14279708HCID 14279708, compound

Product 1

HCID 13849587HCID 13849587, compound

Procedure

In the same manner as described above for the furo[2,3-b]pyridine compound, 6-(4-isopropyl-4-methyl-5-thioxo-2-imidazolin-2-yl)-thieno[2,3-b]pyridine-5-carboxylic acid is prepared in the 37% yield having a mp 242° C.

Workup

  1. customis prepared in the 37% yield

Sources & evidence

ORD record
ord-b958a980db1440b0b6027d62855c7079
Source dataset
uspto-grants-1990_04
Patent number
US04920226

Reaction notes

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