HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,5-Dimethoxyaniline → 3a,4-Dihydro-6,8-dihydroxy-2H,3H-pyrrolo[1,2-a]quinoline-1,5-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,5-Dimethoxyaniline | HCID 66301 | — |
| Reactant | Diethyl 3-oxoadipate | HCID 81576 | — |
| Product | 3a,4-Dihydro-6,8-dihydroxy-2H,3H-pyrrolo[1,2-a]quinoline-1,5-dione | HCID 13366705 | 77% |
Reaction Steps
By the procedures of Examples 2 and 3, diethyl 3-oxohexanedioate [Tetrahedron 23, p. 897 (1967)] and 3,5-dimethoxyaniline were converted to title product, recrystallized from ethyl acetate/cyclohexane, in 77% yield, m.p. 254°-256° C.; m/e 233 (m+); ir (KBr) 3448, 2857, 1680, 1639 cm-1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04920221 |
| Source dataset | uspto-grants-1990_04 |
| ORD ID | ord-9ccfbc889dca4f69a655657691393c4b |
| Source note | uspto-grants-1990_04 |