HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2074018Generated: November 1, 2026
Water → Methyl 3-(3-(2-quinolinylmethyloxy)phenoxymethyl)benzoate
https://huagongshe.com/reaction/2074018
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Phenol, 3-(2-quinolinylmethoxy)- | HCID 10988736 | — |
| Product | Methyl 3-(3-(2-quinolinylmethyloxy)phenoxymethyl)benzoate | HCID 10111528 | — |
Reaction Steps
A mixture of 3-(2-quinolinylmethyloxy)phenol (2.51 g, 0.01 mol), 1.85 g (0.01 mol) of methyl 3-chloromethyl benzoate, and 1.5 g of potassium carbonate in 30 ml of DMF is heated at 50° C. overnight. The reaction mixture is poured into water, extracted with ethyl acetate and the organic solution separated, dried and evaporated to dryness. Recrystallization from ethyl acetate gives methyl 3-(3-(2-quinolinylmethyloxy)phenoxymethyl)benzoate. (M.P. 93°-94° C.)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04920132 |
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| Source dataset | uspto-grants-1990_04 |
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| ORD ID | ord-f69239f6288e42bfa74f337ccae26342 |
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| Source note | uspto-grants-1990_04 |
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