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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2074027Generated: October 31, 2026

Acetic Acid → HCID 14774159, compound

https://huagongshe.com/reaction/2074027

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetic AcidHCID 176—
ReactantHCID 14774158HCID 14774158—
SolventEthanolHCID 702—
SolventWaterHCID 962—
SolventSodium HydroxideHCID 14798—
ProductHCID 14774159HCID 14774159—

Reaction Conditions

Temperature70 °C

Reaction Steps

A mixture of 1 g of ethyl [5-(4-(3-(2-quinolinylmethyloxy)phenoxymethyl)phenyl)tetrazol-3-yl]acetate in 5 ml ethanol and 40 ml of 1N NaOH is stirred at 70° C. for 4 hours. This is cooled, diluted with water, acidified with acetic acid, filtered, washed with water, and then ethyl acetate to give 5-(4-(3-(2-quinolinylmethyloxy)phenoxymethyl)phenyl)tetrazol-3-yl acetic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04920132
Source datasetuspto-grants-1990_04
ORD IDord-708e300bbf58402e8067f2d66e88cb7b
Source noteuspto-grants-1990_04