HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2074078Generated: October 31, 2026
1-(2-Pyridyl)piperazine → HCID 59763826, compound
https://huagongshe.com/reaction/2074078
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 1-(2-Pyridyl)piperazine | HCID 94459 | — |
| Reactant | ethyl 1-ethyl-4-nitro-1H-imidazole-2-carboxylate | HCID 45095100 | — |
| Product | HCID 59763826 | HCID 59763826 | — |
Reaction Steps
A mixture of 1.23 g (5.06 mmol) of ethyl 1-ethyl-4-nitro-1H-imidazole-2-carboxylate (prepared in analogy to Example 10A) and 2.48 g (15.2 mmol) of N-(pyridin-2-yl)piperazine is stirred at 100° C. overnight. For the work-up, the crude mixture obtained is purified by preparative HPLC. 0.724 g (43% of theory) of product are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07919489B2 |
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| Source dataset | uspto-grants-2011_04 |
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| ORD ID | ord-7b820546f2d545e2821f6791b2f5d07c |
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| Source note | uspto-grants-2011_04 |
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