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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2074381Generated: October 26, 2026

Chloropyrazine → tert-Butyl 2-((pyrazin-2-ylamino)methyl)piperidine-1-carboxylate

https://huagongshe.com/reaction/2074381

Reaction equation

Participants

RoleNameHCIDCharge
ReactantChloropyrazineHCID 73277—
Reactanttert-Butyl 2-(aminomethyl)piperidine-1-carboxylateHCID 2756482—
Producttert-Butyl 2-((pyrazin-2-ylamino)methyl)piperidine-1-carboxylateHCID 71631689—

Reaction Steps

The title compound (0.18 g) was prepared from (RS) 2-aminomethyl-piperidine-1-carboxylic acid tert butyl ester (0.54 g) and 2-chloropyrazine according to the method of D20.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07919507B2
Source datasetuspto-grants-2011_04
ORD IDord-7e87c921347141d08fbc933de2aab06c
Source noteuspto-grants-2011_04