N-isopropyl-1-piperazineacetamide → HCID 67092103, compound

HRID 2074730Notes

Reaction equation

HRID 2074730 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([C:28]([F:31])([F:30])[F:29])=[C:6]([CH:27]=1)[CH2:7][N:8]1[CH2:13][CH2:12][NH:11][C:10]2[N:14]=[CH:15][C:16]([C:18]3[CH:19]=[C:20]([CH:24]=[CH:25][CH:26]=3)[C:21]([OH:23])=O)=[CH:17][C:9]1=2.[N:32]1([CH2:38][C:39]([NH:41][CH:42]([CH3:44])[CH3:43])=[O:40])[CH2:37][CH2:36][NH:35][CH2:34][CH2:33]1>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([C:28]([F:29])([F:31])[F:30])=[C:6]([CH:27]=1)[CH2:7][N:8]1[CH2:13][CH2:12][NH:11][C:10]2[N:14]=[CH:15][C:16]([C:18]3[CH:19]=[C:20]([CH:24]=[CH:25][CH:26]=3)[C:21]([N:35]3[CH2:34][CH2:33][N:32]([CH2:38][C:39]([NH:41][CH:42]([CH3:44])[CH3:43])=[O:40])[CH2:37][CH2:36]3)=[O:23])=[CH:17][C:9]1=2

Participants

3

Reactant 2

HCID 100826N-isopropyl-1-piperazineacetamideHCID 583278073-{1-[5-Chloro-2-(trifluoromethyl)benzyl]-1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-7-yl}benzoic acid

Product 1

HCID 67092103HCID 67092103, compound

Procedure

3-{1-[5-chloro-2-(trifluoromethyl)benzyl]-1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-7-yl}benzoic acid was reacted with 2-piperazinyl-N-isopropylacetamide as in General Procedure 10 to give the title compound. LCMS: m/z=615.01 (M+H+); retention time=0.61 minutes.

Sources & evidence

ORD record
ord-d13bbcf04e024668b09528038d288611
Source dataset
uspto-grants-2011_04
Patent number
US07919502B2

Reaction notes

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