HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 56974531, compound → HCID 21356686, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 56974531 | HCID 56974531 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 21356686 | HCID 21356686 | — |
Reaction Steps
A solution of (4-Cyano-2,2-dimethyl-butyl)-[(2R,3S)-3-([1,3]dioxan-5-yloxycarbonylamino)-2-hydroxy-4-phenyl-butyl]-carbamic acid benzyl ester (0.420 g, 0.76 mmol) in EtOAc at ambient temperature was treated with palladium on carbon (0.050 g) and stirred under a balloon of hydrogen. After stirring 16 h the mixture was filtered and solvent was removed in vacuo to give desired product as a colorless oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07919523B2 |
| Source dataset | uspto-grants-2011_04 |
| ORD ID | ord-e7e7932764254a1d822188ba76341c1f |
| Source note | uspto-grants-2011_04 |