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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2074949Generated: October 29, 2026

HCID 56974531, compound → HCID 21356686, compound

https://huagongshe.com/reaction/2074949

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 56974531HCID 56974531—
ReactantHCID 178418361HCID 178418361—
CatalystPalladiumHCID 23938—
SolventEthyl AcetateHCID 8857—
ProductHCID 21356686HCID 21356686—

Reaction Steps

A solution of (4-Cyano-2,2-dimethyl-butyl)-[(2R,3S)-3-([1,3]dioxan-5-yloxycarbonylamino)-2-hydroxy-4-phenyl-butyl]-carbamic acid benzyl ester (0.420 g, 0.76 mmol) in EtOAc at ambient temperature was treated with palladium on carbon (0.050 g) and stirred under a balloon of hydrogen. After stirring 16 h the mixture was filtered and solvent was removed in vacuo to give desired product as a colorless oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07919523B2
Source datasetuspto-grants-2011_04
ORD IDord-e7e7932764254a1d822188ba76341c1f
Source noteuspto-grants-2011_04