Methyl iodide → HCID 58968623, compound

Participants

Reaction Steps

This compound was prepared by an analogous series of reactions to that used for the preparation of N-(2-(1-cyclopentyl-2-methoxypropan-2-yl)-5-(trifluoromethyl)benzyl)-N-(3,5-bis(trifluoromethyl)benzyl)-2-methyl-2H-tetrazol-5-amine from 2-((3,5-bis(trifluoromethyl)benzyl)(2-methyl-2H-tetrazole-5-yl)amino)methyl)-4-(trifluoromethyl)benzonitrile by the addition of cycloheptylmagnesium bromide followed by methylmagnesium bromide then alkylation with methyl iodide LC-MS calc 637.5, found 606 (M-OCH3).

Provenance & Evidence