2-Cyclohexen-1-one, 4,4-dimethyl- → Cyclohexanone, 4,4-dimethyl-

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Reaction Steps

4,4-Dimethylcyclohexanone was prepared by a procedure similar to that described in patent ref: PCT Int. Appl. 2005005456 20, January 2005. 4,4-Dimethylcyclohex-2-enone (3.5 g, 28.18 mmol) was dissolved in ethyl acetate (50 mL). The solution was shaken for 45 minutes under an atmosphere of hydrogen (10 p.s.i.). The completion of the reaction was established by GC-MS then the solution was filtered through a pad of celite and rinsed through with ethyl acetate. The solvent was removed under reduced pressure to give a clear colorless oil which crystallized on standing (3.45 gm, 97%). 1H NMR (400 MHz, CDCl3) δ 2.29 (m, 4H) 1.61 (m, 4H) 1.04 (s, 6H). MS calc 126.5, found 127.1 (M+H).

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