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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2075229Generated: October 31, 2026

Methyl 1-(4-ethynyl-3-fluorobenzyl)azetidine-3-carboxylate → HCID 58415393, compound

https://huagongshe.com/reaction/2075229

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 1-(4-ethynyl-3-fluorobenzyl)azetidine-3-carboxylateHCID 25254788—
ReactantHCID 58415368HCID 58415368—
ProductHCID 58415393HCID 58415393—

Reaction Steps

Synthesized according to Scheme B3 and general procedure G from 2-iodo-4-(pyridin-3-ylmethyl)phenol (0.305 g, 0.98 mmol) and methyl 1-(4-ethynyl-3-fluorobenzyl)azetidine-3-carboxylate (0.220 g, 0.89 mmol): yellow solid. MS (ESI) m/z: Calculated: 430.2; Observed: 431.5 (M++1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07919519B2
Source datasetuspto-grants-2011_04
ORD IDord-284d0cbe101144ecb40db2f3e2848ff3
Source noteuspto-grants-2011_04