HCID 86607048, compound → HCID 58687767, compound

Participants

Reaction Steps

To Compound 52 (106 mg, 0.079 mmol), 5% hydrated trifluoroacetic acid (0.54 ml) was added at room temperature, and this was followed by stirring for 5 minutes. Toluene (about 1 ml) was added; after concentration under reduced pressure, the concentrate was purified by silica gel column chromatography (Yamazen YFLC Gel, eluent; chloroform solution containing 2% methanol-chloroform solution containing 3% methanol-chloroform solution containing 5% methanol) to yield Compound 53 (light-yellow oil 79 mg, 78%).

Provenance & Evidence