HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethylamine hydrochloride → HCID 11587880, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethylamine hydrochloride | HCID 11198 | — |
| Reactant | HCID 76850762 | HCID 76850762 | — |
| Solvent | Dichloromethane methanol | HCID 21226129 | — |
| Product | HCID 11587880 | HCID 11587880 | — |
Reaction Steps
Treat 5-formyl-3-phenylsulfanyl-1H-indole-2-carboxylic acid amide 13 (m=0, R3=Ph) (80 mg, 0.27 mmol) with ethylamine hydrochloride (23.9 mg, 0.30 mmol) as described in General Procedure X to afford Iad (53.0 mg, 60.4%) as an ivory colored solid, tlc Rf=0.1 (10% MeOH/CH2Cl2−0.2% Et3N), m/z obs=326 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07923466B2 |
| Source dataset | uspto-grants-2011_04 |
| ORD ID | ord-8bfbf3acb17141299341ae75e1ab71f4 |
| Source note | uspto-grants-2011_04 |