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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 207588Generated: October 31, 2026

Tetrahydrofuran → tert-Butyl 4-fluoro-4-(hydroxymethyl)piperidine-1-carboxylate

https://huagongshe.com/reaction/207588

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantLithium ionHCID 28486—
ReactantAluminum CationHCID 104727—
ReactantHydrideHCID 166653—
ReactantEthyl N-Boc-4-fluoropiperidine-4-carboxylateHCID 21306965—
Producttert-Butyl 4-fluoro-4-(hydroxymethyl)piperidine-1-carboxylateHCID 22248400—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-b5ee3cee471e4fcb987b07a405c75734
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)