m-Chloroperbenzoic acid → HCID 67096450, compound

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Reaction Steps

A mixture of 3-(4-benzyloxy-5-methoxy-2-methylsulfanyl-phenyl)-5-methyl-[1,2,4]oxadiazole, m-chloroperbenzoic acid (60%, 1.43 g) and methylene chloride (30 mL) was stirred overnight. An aqueous solution of sodium hydrogen sulfite and methylene chloride were added to the mixture. The separated organic layer was washed with a 2 mol/L aqueous solution of sodium hydroxide and brine successively, dried over anhydrous magnesium sulfate, and concentrated under reduced pressure to give 3-(4-benzyloxy-2-methanesulfonyl-5-methoxyphenyl)-5-methyl-[1,2,4]oxa-diazole.

Provenance & Evidence