tert-Butoxy bis(dimethylamino)methane → HCID 67096291, compound

HRID 2076045Notes

Reaction equation

HRID 2076045 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([C:9]2([CH2:16][CH2:17][CH3:18])[CH2:14][CH2:13][CH2:12][CH2:11][C:10]2=[O:15])[CH:6]=[CH:7][CH:8]=1.C(O[CH:24](N(C)C)[N:25]([CH3:27])[CH3:26])(C)(C)C>>[CH3:24][N:25]([CH3:27])[CH:26]=[C:11]1[C:10](=[O:15])[C:9]([C:5]2[CH:6]=[CH:7][CH:8]=[C:3]([O:2][CH3:1])[CH:4]=2)([CH2:16][CH2:17][CH3:18])[CH2:14][CH2:13][CH2:12]1

Participants

3

Reactant 2

HCID 79885tert-Butoxy bis(dimethylamino)methaneHCID 670959582-(3-Methoxy-phenyl)-2-propyl-cyclohexanone

Product 1

HCID 67096291HCID 67096291, compound

Procedure

2-(3-Methoxy-phenyl)-2-propyl-cyclohexanone (101 mg, 0.41 mmol) was reacted with tert.-butoxy-bis-(dimethylamino)-methane using in analogous manner the procedure described in example 45a) to give crude title compound (124 mg) as red oil which was used directly in the next step. MS ISP (m/e): 302.1 [(M+H)+].

Sources & evidence

ORD record
ord-6faab3625edf4a9cb13e47dd56fbb6a1
Source dataset
uspto-grants-2011_04
Patent number
US07923450B2

Reaction notes

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