HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 67096291, compound → [3-Methoxy-4-(4-methyl-imidazol-1-yl)-phenyl]-[8-(3-methoxy-phenyl)-8-propyl-5,6,7,8-tetrahydro-quinazolin-2-yl]-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 67096291 | HCID 67096291 | — |
| Reactant | HCID 178493228 | HCID 178493228 | — |
| Product | [3-Methoxy-4-(4-methyl-imidazol-1-yl)-phenyl]-[8-(3-methoxy-phenyl)-8-propyl-5,6,7,8-tetrahydro-quinazolin-2-yl]-amine | HCID 57780715 | — |
Reaction Steps
The title compound was prepared from 6-[1-dimethylamino-methylidene]-2-(3-methoxy-phenyl)-2-propyl-cyclohexanone (101 mg, 0.33 mmol) and N-[3-methoxy-4-(4-methyl-imidazol-1-yl)-phenyl]-guanidine dinitrate (124 mg, 0.33 mmol) using in analogous manner the procedure described in example 45b). Obtained as white solid (24 mg, 15%). MS ISP (m/e): 484.5 [(M+H)+]. mp 166-168° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07923450B2 |
| Source dataset | uspto-grants-2011_04 |
| ORD ID | ord-dff8163687914af19bc4748f6849805d |
| Source note | uspto-grants-2011_04 |