Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2076046Generated: October 31, 2026

HCID 67096291, compound → [3-Methoxy-4-(4-methyl-imidazol-1-yl)-phenyl]-[8-(3-methoxy-phenyl)-8-propyl-5,6,7,8-tetrahydro-quinazolin-2-yl]-amine

https://huagongshe.com/reaction/2076046

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 67096291HCID 67096291—
ReactantHCID 178493228HCID 178493228—
Product[3-Methoxy-4-(4-methyl-imidazol-1-yl)-phenyl]-[8-(3-methoxy-phenyl)-8-propyl-5,6,7,8-tetrahydro-quinazolin-2-yl]-amineHCID 57780715—

Reaction Steps

The title compound was prepared from 6-[1-dimethylamino-methylidene]-2-(3-methoxy-phenyl)-2-propyl-cyclohexanone (101 mg, 0.33 mmol) and N-[3-methoxy-4-(4-methyl-imidazol-1-yl)-phenyl]-guanidine dinitrate (124 mg, 0.33 mmol) using in analogous manner the procedure described in example 45b). Obtained as white solid (24 mg, 15%). MS ISP (m/e): 484.5 [(M+H)+]. mp 166-168° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07923450B2
Source datasetuspto-grants-2011_04
ORD IDord-dff8163687914af19bc4748f6849805d
Source noteuspto-grants-2011_04