tert-Butoxy bis(dimethylamino)methane → HCID 67095819, compound

HRID 2076051Notes

Reaction equation

HRID 2076051 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH:9]2[CH2:14][CH2:13][CH2:12][CH2:11][C:10]2=[O:15])[CH:5]=[CH:6][C:7]=1[Cl:8].C(O[CH:21](N(C)C)[N:22]([CH3:24])[CH3:23])(C)(C)C>>[CH3:21][N:22]([CH3:24])[CH:23]=[C:11]1[C:10](=[O:15])[CH:9]([C:4]2[CH:5]=[CH:6][C:7]([Cl:8])=[C:2]([Cl:1])[CH:3]=2)[CH2:14][CH2:13][CH2:12]1

Participants

3

Reactant 2

HCID 79885tert-Butoxy bis(dimethylamino)methaneHCID 18441763HCID 18441763, compound

Product 1

HCID 67095819HCID 67095819, compound

Procedure

2-(3,4-Dichloro-phenyl)-cyclohexanone (101 mg, 0.42 mmol) was reacted with tert.-butoxy-bis-(dimethylamino)-methane using in analogous manner the procedure described in example 45a) to give crude title compound (119 mg) as a red oil which was used directly in the next step. MS ISP (m/e): 298.0 [(M+H)+].

Sources & evidence

ORD record
ord-0f8766ffa22f49c59b389cdb53c88e78
Source dataset
uspto-grants-2011_04
Patent number
US07923450B2

Reaction notes

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