tert-Butoxy bis(dimethylamino)methane → HCID 67095891, compound

HRID 2076067Notes

Reaction equation

HRID 2076067 reaction equation
[O:1]=[C:2]1[CH2:7][CH2:6][O:5][CH2:4][CH:3]1[C:8]([O:10][CH3:11])=[O:9].C(O[CH:17](N(C)C)[N:18]([CH3:20])[CH3:19])(C)(C)C>>[CH3:17][N:18]([CH3:20])[CH:19]=[C:7]1[CH2:6][O:5][CH2:4][CH:3]([C:8]([O:10][CH3:11])=[O:9])[C:2]1=[O:1]

Participants

3

Reactant 2

HCID 79885tert-Butoxy bis(dimethylamino)methaneHCID 14666555Methyl 4-oxooxane-3-carboxylate

Product 1

HCID 67095891HCID 67095891, compound

Procedure

Methyl 4-oxo-tetrahydro-pyran-3-carboxylate (74 mg, 0.47 mmol) was reacted with tert.-butoxy-bis-(dimethylamino)-methane using in analogous manner the procedure described in example 45a) to give crude title compound (101 mg) as a red oil which was used directly in the next step. MS ISP (m/e): 214.4 [(M+H)+].

Sources & evidence

ORD record
ord-8cc1decb71c14f14a7fe2c9657b005df
Source dataset
uspto-grants-2011_04
Patent number
US07923450B2

Reaction notes

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