反应详情

The title compound was prepared from crude ethyl 3-[1-dimethylamino-methylidene]-2-oxo-cyclohexanecarboxylate (165 mg, 0.5 mmol) and N-[3-fluoro-4-(4-methyl-imidazol-1-yl)-phenyl]-guanidine dinitrate (134 mg, 0.37 mmol) using in analogous manner the procedure described in example 45b). Obtained as an off-white solid (27 mg, 18%). MS ISP (m/e): 396.4 [(M+H)+]. mp 142-145° C.