tert-Butoxy bis(dimethylamino)methane → HCID 67095895, compound

HRID 2076079Notes

Reaction equation

HRID 2076079 reaction equation
[O:1]=[C:2]1[CH2:8][CH2:7][CH2:6][CH2:5][CH2:4][CH:3]1[C:9]([O:11][CH3:12])=[O:10].C(O[CH:18](N(C)C)[N:19]([CH3:21])[CH3:20])(C)(C)C>>[CH3:18][N:19]([CH3:21])[CH:20]=[C:8]1[CH2:7][CH2:6][CH2:5][CH2:4][CH:3]([C:9]([O:11][CH3:12])=[O:10])[C:2]1=[O:1]

Participants

3

Reactant 2

HCID 79885tert-Butoxy bis(dimethylamino)methaneHCID 288225Methyl 2-oxocycloheptane-1-carboxylate

Product 1

HCID 67095895HCID 67095895, compound

Procedure

Methyl 2-oxo-cycloheptanecarboxylate (51 mg, 0.30 mmol) was reacted with tert.-butoxy-bis-(dimethylamino)-methane using in analogous manner the procedure described in example 45a) to give crude title compound (85 mg) as a yellow oil which was used directly in the next step. MS ISP (m/e): 226.3 [(M+H)+].

Sources & evidence

ORD record
ord-e836125993a94f8691ad76f696064823
Source dataset
uspto-grants-2011_04
Patent number
US07923450B2

Reaction notes

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