HCID 67095917, compound → HCID 44194154, compound

Participants

Reaction Steps

The title compound was prepared from crude 2-[1-dimethylamino-meth-(Z)-ylidene]-6-(3,4,5-trifluoro-phenyl)-cyclohexanone (120 mg, 0.42 mmol) and N-[3-methoxy-4-(4-methyl-imidazol-1-yl)-phenyl]-guanidine dinitrate (131 mg, 0.35 mmol) using in analogous manner the procedure described in example 45b). Obtained as a yellow solid (64 mg, 64%). MS ISP (m/e): 466.2 (100) [(M+H)+]. 1H NMR (DMSO-D6, 300 MHz): δ (ppm)=9.57 (s, 1H), 8.36 (s, 1H), 7.60 (m, 2H), 7.01-7.18 (m, 4H), 6.98 (s, 1H), 4.18 (m, 1H), 3.55 (s, 3H), 2.73 (m, 2H), 2.13 (s, 3H), 1.70-2.20 (m, 4H).

Provenance & Evidence