1,1'-Bi(cyclohexyl)-2-one → HCID 67096318, compound

HRID 2076091Notes

Reaction equation

HRID 2076091 reaction equation
[CH:1]1([CH:7]2[CH2:12][CH2:11][CH2:10][CH2:9][C:8]2=[O:13])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.C(O[CH:19](N(C)C)[N:20]([CH3:22])[CH3:21])(C)(C)C>>[CH3:19][N:20]([CH3:22])/[CH:21]=[C:9]1/[C:8](=[O:13])[CH:7]([CH:1]2[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]2)[CH2:12][CH2:11][CH2:10]/1

Participants

3

Reactant 2

HCID 70161,1'-Bi(cyclohexyl)-2-oneHCID 79885tert-Butoxy bis(dimethylamino)methane

Product 1

HCID 67096318HCID 67096318, compound

Procedure

2-Cyclohexylcyclohexanone (99 mg, 0.55 mmol) was reacted with tert.-butoxy-bis-(dimethylamino)-methane using in analogous manner the procedure described in example 45a) to give crude title compound (116 mg) as a brown solid which was used directly in the next step. MS ISP (m/e): 236.2 (100) [(M+H)+].

Sources & evidence

ORD record
ord-d4824e6d4e094692beb8b0418cf6a494
Source dataset
uspto-grants-2011_04
Patent number
US07923450B2

Reaction notes

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