HCID 67095886, compound → HCID 57780704, compound

Participants

Reaction Steps

The title compound was prepared from crude {3-[1-dimethylamino-meth-(E)-ylidene]-2-oxo-cyclohexyl}-acetic acid ethyl ester (108 mg, 0.33 mmol) and N-[3-methoxy-4-(4-methyl-imidazol-1-yl)-phenyl]-guanidine dinitrate (111 mg, 0.30 mmol) using in analogous manner the procedure described in example 45b). Obtained as yellow crystals (83 mg, 66%). MS ISP (m/e): 422.2 (100) [(M+H)+]. 1H NMR (DMSO-D6, 300 MHz): δ (ppm)=9.60 (s, 1H), 8.25 (s, 1H), 7.88 (s, 1H), 7.65 (s, 1H), 7.27 (d, 1H), 7.20 (d, 1H), 7.02 (s, 1H), 4.06 (q, 2H), 3.79 (s, 3H), 3.10 (m, 2H), 2.60-2.70 (m, 3H), 2.14 (s, 3H), 2.02 (m, 1H), 1.86 (m, 1H), 1.65 (m, 2H), 1.15 (t, 3H).

Provenance & Evidence