tert-Butoxy bis(dimethylamino)methane → HCID 67096251, compound

HRID 2076096Notes

Reaction equation

HRID 2076096 reaction equation
[C:1]([Si:5]([CH3:15])([CH3:14])[O:6][CH:7]1[CH2:12][CH2:11][CH2:10][CH2:9][C:8]1=[O:13])([CH3:4])([CH3:3])[CH3:2].C(O[CH:21](N(C)C)[N:22]([CH3:24])[CH3:23])(C)(C)C>>[C:1]([Si:5]([CH3:15])([CH3:14])[O:6][CH:7]1[CH2:12][CH2:11][CH2:10]/[C:9](=[CH:21]\[N:22]([CH3:24])[CH3:23])/[C:8]1=[O:13])([CH3:4])([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 79885tert-Butoxy bis(dimethylamino)methaneHCID 111955462-(tert-Butyldimethylsilyloxy)cyclohexanone

Product 1

HCID 67096251HCID 67096251, compound

Procedure

2-(tert.-Butyldimethylsiloxy)cyclohexanone (118 mg, 0.50 mmol) was reacted with tert.-butoxy-bis-(dimethylamino)-methane using in analogous manner the procedure described in example 45a) to give crude title compound (85 mg) as a brown oil which was used directly in the next step. MS ISP (m/e): 284.2 (100) [(M+H)+].

Sources & evidence

ORD record
ord-5cc459c298f04e5798b6b9dc347e28ee
Source dataset
uspto-grants-2011_04
Patent number
US07923450B2

Reaction notes

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