tert-Butoxy bis(dimethylamino)methane → HCID 67095946, compound

HRID 2076104Notes

Reaction equation

HRID 2076104 reaction equation
[N:1]1([CH:7]2[CH2:12][CH2:11][CH2:10][CH2:9][C:8]2=[O:13])[CH2:6][CH2:5][O:4][CH2:3][CH2:2]1.C(O[CH:19](N(C)C)[N:20]([CH3:22])[CH3:21])(C)(C)C>>[CH3:19][N:20]([CH3:22])[CH:21]=[C:9]1[CH2:10][CH2:11][CH2:12][CH:7]([N:1]2[CH2:2][CH2:3][O:4][CH2:5][CH2:6]2)[C:8]1=[O:13]

Participants

3

Reactant 2

HCID 79885tert-Butoxy bis(dimethylamino)methaneHCID 12292874HCID 12292874, compound

Product 1

HCID 67095946HCID 67095946, compound

Procedure

2-Morpholin-4-yl-cyclohexanone (183 mg, 1.0 mmol) was reacted with tert.-butoxy-bis-(dimethylamino)-methane using in analogous manner the procedure described in example 45a) to give crude title compound (260 mg) as a yellow oil which was used directly in the next step.

Sources & evidence

ORD record
ord-6d45570724f7440e8ca8d8cdbfb21f06
Source dataset
uspto-grants-2011_04
Patent number
US07923450B2

Reaction notes

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