HCID 67095946, compound → HCID 57780685, compound

HRID 2076105Notes

Reaction equation

HRID 2076105 reaction equation
CN(C)[CH:3]=[C:4]1[CH2:9][CH2:8][CH2:7][CH:6]([N:10]2[CH2:15][CH2:14][O:13][CH2:12][CH2:11]2)[C:5]1=O.[N+]([O-])(O)=O.[N+]([O-])(O)=O.[CH3:26][O:27][C:28]1[CH:29]=[C:30]([NH:40][C:41]([NH2:43])=[NH:42])[CH:31]=[CH:32][C:33]=1[N:34]1[CH:38]=[C:37]([CH3:39])[N:36]=[CH:35]1>>[CH3:26][O:27][C:28]1[CH:29]=[C:30]([NH:40][C:41]2[N:43]=[CH:3][C:4]3[CH2:9][CH2:8][CH2:7][CH:6]([N:10]4[CH2:11][CH2:12][O:13][CH2:14][CH2:15]4)[C:5]=3[N:42]=2)[CH:31]=[CH:32][C:33]=1[N:34]1[CH:38]=[C:37]([CH3:39])[N:36]=[CH:35]1

Participants

3

Reactant 2

HCID 67095946HCID 67095946, compoundHCID 178493228HCID 178493228, compound

Product 1

HCID 57780685HCID 57780685, compound

Procedure

The title compound was prepared from 2-[1-dimethylamino-methylidene]-6-morpholin-4-yl-cyclohexanone (260 mg, 1.0 mmol) and N-[3-methoxy-4-(4-methyl-imidazol-1-yl)-phenyl]-guanidine dinitrate (223 mg, 0.60 mmol) using in analogous manner the procedure described in example 45b). Obtained as a white solid (38 mg, 15%). MS ISP (m/e): 421.1 (100) [(M+H)+]. mp 214-216° C.

Sources & evidence

ORD record
ord-93054f6bfc8c4e9395c1850496e14eb0
Source dataset
uspto-grants-2011_04
Patent number
US07923450B2

Reaction notes

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