tert-Butoxy bis(dimethylamino)methane → HCID 67095902, compound

HRID 2076110Notes

Reaction equation

HRID 2076110 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[CH:7]1[CH2:12][CH2:11][CH2:10][CH2:9][C:8]1=[O:13].C(O[CH:19](N(C)C)[N:20]([CH3:22])[CH3:21])(C)(C)C>>[CH3:19][N:20]([CH3:22])[CH:21]=[C:9]1[CH2:10][CH2:11][CH2:12][CH:7]([C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][N:1]=2)[C:8]1=[O:13]

Participants

3

Reactant 2

HCID 79885tert-Butoxy bis(dimethylamino)methaneHCID 2768544HCID 2768544, compound

Product 1

HCID 67095902HCID 67095902, compound

Procedure

2-Pyridin-2-yl-cyclohexanone (175 mg, 1.0 mmol) was reacted with tert.-butoxy-bis-(dimethylamino)-methane using in analogous manner the procedure described in example 45a) to give crude title compound (226 mg) as a yellow solid which was used directly in the next step. MS ISP (m/e): 231.4 (100) [(M+H)+].

Sources & evidence

ORD record
ord-74ceb919fba549ab9c0d71d82c102bdb
Source dataset
uspto-grants-2011_04
Patent number
US07923450B2

Reaction notes

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