tert-Butoxy bis(dimethylamino)methane → HCID 67095830, compound

HRID 2076114Notes

Reaction equation

HRID 2076114 reaction equation
[N:1]1([C:7]([CH:9]2[CH2:14][CH2:13][CH2:12][CH2:11][C:10]2=[O:15])=[O:8])[CH2:6][CH2:5][O:4][CH2:3][CH2:2]1.C(O[CH:21](N(C)C)[N:22]([CH3:24])[CH3:23])(C)(C)C>>[CH3:21][N:22]([CH3:24])[CH:23]=[C:11]1[CH2:12][CH2:13][CH2:14][CH:9]([C:7]([N:1]2[CH2:2][CH2:3][O:4][CH2:5][CH2:6]2)=[O:8])[C:10]1=[O:15]

Participants

3

Reactant 2

HCID 79885tert-Butoxy bis(dimethylamino)methaneHCID 113678262-(Morpholine-4-carbonyl)-cyclohexanone

Product 1

HCID 67095830HCID 67095830, compound

Procedure

2-(Morpholine-4-carbonyl)-cyclohexanone (17 mg, 0.08 mmol) was reacted with tert.-butoxy-bis-(dimethylamino)-methane using in analogous manner the procedure described in example 45a) to give crude title compound (16 mg) as a yellow oil which was used directly in the next step. MS ISP (m/e): 267.5 (100) [(M+H)+].

Sources & evidence

ORD record
ord-d31b95b523554ea5857005f2a186c894
Source dataset
uspto-grants-2011_04
Patent number
US07923450B2

Reaction notes

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