HCID 67095830, compound → HCID 57780720, compound

HRID 2076117Notes

Reaction equation

HRID 2076117 reaction equation
CN(C)[CH:3]=[C:4]1[CH2:9][CH2:8][CH2:7][CH:6]([C:10]([N:12]2[CH2:17]COC[CH2:13]2)=[O:11])[C:5]1=O.[N+]([O-])(O)=O.[N+]([O-])(O)=O.[CH3:28][O:29][C:30]1[CH:31]=[C:32]([NH:42][C:43]([NH2:45])=[NH:44])[CH:33]=[CH:34][C:35]=1[N:36]1[CH:40]=[C:39]([CH3:41])[N:38]=[CH:37]1>>[CH3:17][N:12]([CH3:13])[C:10]([CH:6]1[C:5]2[N:45]=[C:43]([NH:42][C:32]3[CH:33]=[CH:34][C:35]([N:36]4[CH:40]=[C:39]([CH3:41])[N:38]=[CH:37]4)=[C:30]([O:29][CH3:28])[CH:31]=3)[N:44]=[CH:3][C:4]=2[CH2:9][CH2:8][CH2:7]1)=[O:11]

Participants

3

Reactant 2

HCID 67095830HCID 67095830, compoundHCID 178493228HCID 178493228, compound

Product 1

HCID 57780720HCID 57780720, compound

Procedure

The title compound was prepared from 2-[1-dimethylamino-methylidene]-6-(morpholine-4-carbonyl)-cyclohexanone (25 mg, 0.11 mmol) and N-[3-methoxy-4-(4-methyl-imidazol-1-yl)-phenyl]-guanidine dinitrate (31 mg, 0.084 mmol) using in analogous manner the procedure described in example 45b). Obtained as a white solid (23 mg, 67%). MS ISP (m/e): 407.4 (100) [(M+H)+]. mp 150-152° C.

Sources & evidence

ORD record
ord-5f66d60cb4ac422fbe6b86c2067ec50c
Source dataset
uspto-grants-2011_04
Patent number
US07923450B2

Reaction notes

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