HCID 67096128, compound → HCID 57780717, compound

HRID 2076120Notes

Reaction equation

HRID 2076120 reaction equation
CN(C)[CH:3]=[C:4]1[CH2:9][CH2:8][CH2:7][CH:6]([C:10]([N:12]2[CH2:16][CH2:15][CH2:14][CH2:13]2)=[O:11])[C:5]1=O.[N+]([O-])(O)=O.[N+]([O-])(O)=O.[CH3:27][O:28][C:29]1[CH:30]=[C:31]([NH:41][C:42]([NH2:44])=[NH:43])[CH:32]=[CH:33][C:34]=1[N:35]1[CH:39]=[C:38]([CH3:40])[N:37]=[CH:36]1>>[CH3:27][O:28][C:29]1[CH:30]=[C:31]([NH:41][C:42]2[N:44]=[CH:3][C:4]3[CH2:9][CH2:8][CH2:7][CH:6]([C:10]([N:12]4[CH2:16][CH2:15][CH2:14][CH2:13]4)=[O:11])[C:5]=3[N:43]=2)[CH:32]=[CH:33][C:34]=1[N:35]1[CH:39]=[C:38]([CH3:40])[N:37]=[CH:36]1

Participants

3

Reactant 2

HCID 67096128HCID 67096128, compoundHCID 178493228HCID 178493228, compound

Product 1

HCID 57780717HCID 57780717, compound

Procedure

The title compound was prepared from 2-[1-dimethylamino-methylidene]-6-(pyrrolidine-1-carbonyl)-cyclohexanone (58 mg, 0.23 mmol) and N-[3-methoxy-4-(4-methyl-imidazol-1-yl)-phenyl]-guanidine dinitrate (64 mg, 0.17 mmol) using in analogous manner the procedure described in example 45b). Obtained as a yellow solid (55 mg, 73%). MS ISP (m/e): 433.3 (100) [(M+H)+]. mp 94-95° C.

Sources & evidence

ORD record
ord-613fc3ec99ec4d17bf67cdf848ddb263
Source dataset
uspto-grants-2011_04
Patent number
US07923450B2

Reaction notes

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