HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 11293976, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 59730742 | HCID 59730742 | — |
| Reactant | tert-Butyl [(6-aminopyridin-3-yl)methyl]carbamate | HCID 59730780 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 11293976 | HCID 11293976 | — |
Reaction Steps
117-C was coupled with 6-[(7-methoxyquinolin-4-yl)oxy]-2-methyl-1-benzofuran-3-carboxylic acid 117-D (as prepared in Scheme II discussed previously). After work up the mixture was treated with 50% TFA in CH2Cl2 to give N-[5-(aminomethyl)pyridin-2-yl]-6-[(7-methoxyquinolin-4-yl)oxy]-2-methyl-1-benzofuran-3-carboxamide 117-E.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07923457B2 |
| Source dataset | uspto-grants-2011_04 |
| ORD ID | ord-0ba076922d2440afae913dbc12b23667 |
| Source note | uspto-grants-2011_04 |