2-Chloro-5-nitroquinoline → HCID 25019064, compound

HRID 2076289Notes

Reaction equation

HRID 2076289 reaction equation
[N+:1]([C:4]1[CH:13]=[CH:12][CH:11]=[C:10]2[C:5]=1[CH:6]=[CH:7][C:8](Cl)=[N:9]2)([O-])=O.[F:15][C:16]1[CH:17]=[C:18]([S:24](Cl)(=[O:26])=[O:25])[CH:19]=[C:20]([F:23])[C:21]=1[F:22].[CH3:28][O:29][C:30]1[CH:38]=[C:37]2[C:33]([CH2:34][CH2:35][CH:36]2[NH2:39])=[CH:32][CH:31]=1>>[F:15][C:16]1[CH:17]=[C:18]([S:24]([NH:1][C:4]2[CH:13]=[CH:12][CH:11]=[C:10]3[C:5]=2[CH:6]=[CH:7][C:8]([NH:39][CH:36]2[C:37]4[C:33](=[CH:32][CH:31]=[C:30]([O:29][CH3:28])[CH:38]=4)[CH2:34][CH2:35]2)=[N:9]3)(=[O:26])=[O:25])[CH:19]=[C:20]([F:23])[C:21]=1[F:22]

Participants

4

Reactant 3

HCID 3192512-Chloro-5-nitroquinolineHCID 27788583,4,5-Trifluorobenzenesulfonyl chlorideHCID 99204636-Methoxy-1-Indanamine

Product 1

HCID 25019064HCID 25019064, compound

Procedure

The title compound, MS: m/e=500.4 (M+H+), was prepared in accordance with the general method of example 13 from 5-nitro-2-chloroquinoline, 3,4,5-trifluorobenzenesulfonyl chloride and 6-methoxyindan-1-ylamine (CAS 103028-81-5).

Sources & evidence

ORD record
ord-cb6b579503dd4059a7dfa3cfad9aa33a
Source dataset
uspto-grants-2011_04
Patent number
US07923561B2

Reaction notes

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