3-Pyridinemethanamine → HCID 25019061, compound

HRID 2076290Notes

Reaction equation

HRID 2076290 reaction equation
I[C:2]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:3]=1[CH:4]=[CH:5][C:6](Cl)=[N:7]2.[O:13]1[C:17]2[CH:18]=[CH:19][CH:20]=[CH:21][C:16]=2[CH:15]([NH2:22])[CH2:14]1.[NH2:23][CH2:24][C:25]1[CH:26]=[N:27][CH:28]=[CH:29][CH:30]=1>>[O:13]1[C:17]2[CH:18]=[CH:19][CH:20]=[CH:21][C:16]=2[CH:15]([NH:22][C:6]2[CH:5]=[CH:4][C:3]3[C:2]([NH:23][CH2:24][C:25]4[CH:26]=[N:27][CH:28]=[CH:29][CH:30]=4)=[CH:11][CH:10]=[CH:9][C:8]=3[N:7]=2)[CH2:14]1

Participants

4

Reactant 3

HCID 310183-PyridinemethanamineHCID 137781522,3-Dihydro-1-benzofuran-3-amineHCID 457894242-Chloro-5-iodoquinoline

Product 1

HCID 25019061HCID 25019061, compound

Procedure

The title compound, MS: m/e=369.0 (M+H+), was prepared in accordance with the general method of example 6 from 5-iodo-2-chloroquinoline, rac-2,3-dihydro-benzofuran-3-ylamine (CAS 109926-35-4) and 3-(aminomethyl)pyridine.

Sources & evidence

ORD record
ord-a429e5c1294f45d1b0a6eac86ae894a2
Source dataset
uspto-grants-2011_04
Patent number
US07923561B2

Reaction notes

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