4-Fluorobenzenesulfonyl chloride → HCID 25019325, compound

HRID 2076292Notes

Reaction equation

HRID 2076292 reaction equation
[N+:1]([C:4]1[CH:13]=[CH:12][CH:11]=[C:10]2[C:5]=1[CH:6]=[CH:7][C:8](Cl)=[N:9]2)([O-])=O.[F:15][C:16]1[CH:21]=[CH:20][C:19]([S:22](Cl)(=[O:24])=[O:23])=[CH:18][CH:17]=1.[CH3:26][O:27][C:28]1[CH:36]=[C:35]2[C:31]([CH2:32][CH2:33][CH:34]2[NH2:37])=[CH:30][CH:29]=1>>[F:15][C:16]1[CH:21]=[CH:20][C:19]([S:22]([NH:1][C:4]2[CH:13]=[CH:12][CH:11]=[C:10]3[C:5]=2[CH:6]=[CH:7][C:8]([NH:37][CH:34]2[C:35]4[C:31](=[CH:30][CH:29]=[C:28]([O:27][CH3:26])[CH:36]=4)[CH2:32][CH2:33]2)=[N:9]3)(=[O:24])=[O:23])=[CH:18][CH:17]=1

Participants

4

Reactant 3

HCID 95884-Fluorobenzenesulfonyl chlorideHCID 3192512-Chloro-5-nitroquinolineHCID 99204636-Methoxy-1-Indanamine

Product 1

HCID 25019325HCID 25019325, compound

Procedure

The title compound, MS: m/e=464.1 (M+H+), was prepared in accordance with the general method of example 13 from 5-nitro-2-chloroquinoline, 4-fluorobenzenesulfonyl chloride and 6-methoxyindan-1-ylamine (CAS 103028-81-5).

Sources & evidence

ORD record
ord-90543658e1a3481ea472680485deb871
Source dataset
uspto-grants-2011_04
Patent number
US07923561B2

Reaction notes

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